Potencial terapéutico de las chalconas en la lucha contra el dengue: análisis bibliométrico

Autores/as

• Danúbio Andrade Bezerra Farias Rede Nordeste de Biotecnologia, Programa de Pós-Graduação em Biotecnologia, Universidade Estadual do Ceará, Campus do Itaperi, Fortaleza, Ceará, Brasil. Laboratório de Biotecnologia e Biologia Molecular, Universidade Estadual do Ceará, Campus do Itaperi, Fortaleza, Ceará, Brasil. https://orcid.org/0009-0009-0009-985X
• Luiz Francisco Wemmenson Gonçalves Moura Rede Nordeste de Biotecnologia, Programa de Pós-Graduação em Biotecnologia, Universidade Estadual do Ceará, Campus do Itaperi, Fortaleza, Ceará, Brasil. Laboratório de Biotecnologia e Biologia Molecular, Universidade Estadual do Ceará, Campus do Itaperi, Fortaleza, Ceará, Brasil. https://orcid.org/0000-0001-5854-6709
• Natália do Vale Canabrava Rede Nordeste de Biotecnologia, Programa de Pós-Graduação em Biotecnologia, Universidade Estadual do Ceará, Campus do Itaperi, Fortaleza, Ceará, Brasil. Laboratório de Biotecnologia e Biologia Molecular, Universidade Estadual do Ceará, Campus do Itaperi, Fortaleza, Ceará, Brasil. https://orcid.org/0000-0002-4841-8989
• Francisco Leandro Fernandes Sampaio Laboratório de Biotecnologia e Biologia Molecular, Universidade Estadual do Ceará, Campus do Itaperi, Fortaleza, Ceará, Brasil. https://orcid.org/0009-0007-4043-6238
• José Ítalo Magalhães de Sousa Laboratório de Biotecnologia e Biologia Molecular, Universidade Estadual do Ceará, Campus do Itaperi, Fortaleza, Ceará, Brasil. https://orcid.org/0009-0008-7305-6714
• Vânia Marilande Ceccatto Rede Nordeste de Biotecnologia, Programa de Pós-Graduação em Biotecnologia, Universidade Estadual do Ceará, Campus do Itaperi, Fortaleza, Ceará, Brasil. Fisiologia Ciências, Programa de Pós-Graduação, Universidade Estadual do Ceará, Campus do Itaperi, Fortaleza, Ceará, Brasil. https://orcid.org/0000-0003-4839-4400
• Márcia Maria Mendes Marques Duque Universidade Federal do Piauí, Campus Senador Helvídio Nunes de Barros, Piauí, Brasil. https://orcid.org/0000-0001-7661-2570
• Maria Izabel Florindo Guedes Rede Nordeste de Biotecnologia, Programa de Pós-Graduação em Biotecnologia, Universidade Estadual do Ceará, Campus do Itaperi, Fortaleza, Ceará, Brasil. Laboratório de Biotecnologia e Biologia Molecular, Universidade Estadual do Ceará, Campus do Itaperi, Fortaleza, Ceará, Brasil. Fisiologia Ciências, Programa de Pós-Graduação, Universidade Estadual do Ceará, Campus do Itaperi, Fortaleza, Ceará, Brasil. https://orcid.org/0000-0002-4569-8663

DOI:

https://doi.org/10.17058/reci.v16i.20407

Palabras clave:

Estudio Bibliométrico, Bibliometrix, Chalcona, Dengue, Aedes aegypti

Resumen

Justificación y Objetivos: El dengue es una enfermedad viral transmitida por el mosquito Aedes aegypti, caracterizada por su rápida propagación e impacto global. Además del dengue, este vector también es responsable de la transmisión de los virus del Zika y el Chikunguña. Dada la limitada disponibilidad de terapias antivirales, el desarrollo de nuevos tratamientos es crucial. Los compuestos de chalcona han demostrado potencial larvicida y antiviral, lo que los convierte en candidatos prometedores en la lucha contra estas enfermedades.  Este estudio busca realizar una revisión bibliográfica sobre el potencial terapéutico de las chalconas en la lucha contra el dengue mediante análisis bibliométrico. Contenido:El análisis bibliométrico se realizó utilizando la base de datos Scopus para identificar publicaciones tanto globales como nacionales. La recopilación de datos incluyó estrategias de búsqueda booleana y filtros específicos, y los documentos recuperados se analizaron mediante la herramienta Bibliometrix para evaluar las principales tendencias de investigación, las redes de colaboración y la contribución de Brasil al campo. El análisis destaca los principales dominios de investigación, las contribuciones de los autores, las afiliaciones institucionales y las tendencias de publicación por país. Mediante el análisis de publicaciones de 2006 a 2024, el estudio identifica las áreas de investigación más destacadas, los autores principales, las revistas influyentes y las contribuciones específicas de cada país. Conclusión: Los hallazgos revelan una creciente producción científica sobre las chalconas y el dengue, con estudios pioneros que subrayan su potencial antiviral. El estudio también mapea las redes de colaboración global, contribuyendo a los avances en el descubrimiento de antivirales y el control de vectores.

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