Association of Quick Sofa and Systemic Inflammatory Response Syndrome with mortality in septic patients

Authors

DOI:

https://doi.org/10.17058/reci.v15i2.19543

Abstract

Background and Objective: sepsis, a life-threatening condition, requires early identification. The Quick Sofa score may contribute to identifying the risk of sepsis in patients admitted to the emergency department. However, these scores and criteria need extensive testing before being implemented in clinical practice. This study aimed to evaluate the association between the Quick Sofa score and the Systemic Inflammatory Response Syndrome criteria with mortality in critically ill septic patients from a university hospital. Methods: a retrospective observational study including 614 patients aged over 18 years, admitted to the intensive care unit due to sepsis or septic shock. Results: no statistically significant differences were observed in the Quick Sofa or the Systemic Inflammatory Response Syndrome between survivors and non-survivors. Patients with a Quick Sofa score ≥2 were associated with the development of septic shock (p=0.00). Patients scoring ≥2 on Systemic Inflammatory Response Syndrome criteria showed a significant association with intensive care unit stays longer than 72 hours (p=0.013). Conclusion: the scores and criteria evaluated were not associated with mortality in septic patients. High mortality rates and the incidence of septic shock highlight the need for more effective tools for early diagnosis of sepsis.

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Author Biographies

  • Vanessa Frighetto Bonatto, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul.

    Enfermeira da Emergência Adulto do Hospital de Clínicas de Porto Alegre. Bacharel em Enfermagem pela Universidade Federal do Rio Grande do Sul. Especialista em Terapia Intensiva. Mestrado em andamento pela Universidade Federal do Rio Grande do Sul.

  • Jaqueline Sangiogo Haas, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul.

    Enfermeira do Centro de Terapia Intensiva Adulto e do Programa Intra Hospitalar de Combate à Sepse do Hospital de Clínicas de Porto Alegre. Especialista em Terapia Intensiva pela Associação Brasileira de Enfermagem em Terapia Intensiva (ABENTI) e Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS). Mestre em Ciências Médicas pela Faculdade de Medicina da Universidade Federal do Rio Grande do Sul.

  • Miriane Melo Silveira Moretti, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul.

    Enfermeira do Centro de Terapia Intensiva Adulto do Hospital de Clínicas de Porto Alegre. Especialista em Terapia Intensiva. Mestre em Enfermagem Profissional pela Universidade do Vale do Rio dos Sinos (UNISINOS). Doutorado em andamento pela Universidade Federal do Rio Grande do Sul.

  • Arianne dos Santos Gomes, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul.

    Estudante do 8º semestre do bacharelado em Enfermagem da UFRGS. Experiência como estagiária administrativa da Unidade de Terapia Intensiva Adulta e assistencial da Unidade de Oncologia Pediátrica do Hospital de Clínicas de Porto Alegre. Atua como bolsista de iniciação científica sob orientação da professora Dra. Karina de Oliveira Azzolin.

  • Rafael Barbarena Moraes, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul.

    Médico intensivista do Centro de Terapia Intensiva Adulto do Hospital de Clínicas de Porto Alegre. Graduado em Medicina pela UFRGS. Residência em Medicina Interna pelo Hospital Nossa Senhora da Conceição (2003) e Medicina Intensiva pelo Hospital de Clínicas de Porto Alegre (2005). Especialista em Medicina Intensiva pela AMIB (2006). Mestre em Endocrinologia pela UFRGS (2009). Doutor em Endocrinologia pela UFRGS (2009). Professor do Programa de Pós-Graduação em Pneumologia da UFRGS. Médico do Programa Intra Hospitalar de Combate à Sepse e Supervisor do Programa de Residência Médica em Medicina Intensiva do Hospital de Clínicas de Porto Alegre.

  • Gilberto Friedmann, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul.

    Professor titular da UFRGS e coordenador do programa de Pós Graduação em Ciências Pneumológicas da UFRGS. Graduação em Medicina pela UFRGS (1982). Mestre em Ciências Médicas pela UFRGS (1990). Doutor em Ciências da Saúde: Cardiologia e Ciências Cardiovasculares pela UFRGS (1995). Experiência como professor Adjunto da Faculdade Federal de Ciências Médicas de Porto Alegre (2006 - 2019). Experiência como coordenação da Comissão de Graduação da Medicina da UFRGS. Foi editor-chefe da Revista Brasileira de Terapia Intensiva e da Revista Científica Clinical Biomedical Research, jornal oficial da FAMED-HCPA.

  • Karina de Oliveira Azzolin, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul.

    Professora adjunta da Escola de Enfermagem da Universidade Federal do Rio Grande do Sul, do departamento de Enfermagem Médico-Cirúrgica. Chefia do Serviço de Enfermagem em Terapia Intensiva do Hospital de Clínicas de Porto Alegre.

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Published

2025-05-08

Issue

Vol. 15 No. 2 (2025)

Section

ORIGINAL ARTICLE

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Copyright (c) 2025 Vanessa Frighetto Bonatto, Jaqueline Sangiogo Haas, Miriane Melo Silveira Moretti; Arianne dos Santos Gomes; Rafael Barbarena Moraes, Gilberto Friedmann, Karina Azzolin

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How to Cite

Association of Quick Sofa and Systemic Inflammatory Response Syndrome with mortality in septic patients. (2025). Revista De Epidemiologia E Controle De Infecção, 15(2). https://doi.org/10.17058/reci.v15i2.19543