Epidemiological and clinical characteristics of sepse in a public hospital of Paraná

Authors

• Franciele Nascimento Santos Zonta Universidade Paranaense
• Patricia Gurgel Amaral Velasquez Universidade Parananense
• Leonardo Garcia Velasquez Universidade Paranaense
• Luciana Savi Demetrio Universidade Paranaense
• Danieli Miranda Universidade Paranaense
• Mirian Carla Bortolamedi Diamenes Silva Hospital Regional do Sudoeste do Paraná

DOI:

https://doi.org/10.17058/reci.v8i3.11438

Abstract

Background and Objective: Sepsis is a public health problem that causes clinical and economic impact. The objective of this study was to identify the epidemiological and clinical characteristics of sepsis in a public hospital. Methods: This is an exploratory field research, documental, retrospective, with quantitative approach. Data were collected from patients admitted to the Intensive Care Unit from January 2012 to January 2017, for which a checklist with clinical and demographic variables was used. We included all patients from hospitalized patients who had sepsis at the time of admission or after admission. Descriptive frequency analysis, Distribution of previous variables and significance were obtained by the Chi-square test. Results: Of a total of 1,557 medical records, 1112 (71,4%) were included in the study, which were classified as Systemic inflammatory response syndrome (13,9%) sepsis (39,1%) or septic shock (47,0%). There was a predominance of male patients (55.8%), older than 70 years (36.3%) and white (92.6%). The prevalence of hospitalization was up to one week (50.4%). Prevalence of clinical patients (42.4%), with nosocomial infection found in 50.2% of the cases. The main sources of infection were lung (32.9%) and surgical wound (23.5%). Among the causes of admission, respiratory complications (19.5%) and polytrauma (9.3%) prevailed. Cultures were positive in 29.7% of the cases, mostly gram negative bacilli (12.1%). Mortality in SIRS, sepsis and septic shock was 0.3%, 30.1%, 33.0%, respectively. Conclusion: The study evidenced that sepsis affected mostly male elderly, and that the infectious focus was of pulmonary origin in the nosocomial scope. There were still high mortality rates, especially in cases of septic shock.